Molecular identification of adenoviruses in clinical samples by analyzing a partial hexon genomic region.
نویسندگان
چکیده
Here we present a system for adenovirus detection and genotyping based on PCR amplification and phylogenetic analysis of a conserved hexon gene fragment. The system was validated using 157 sequences (86 previously typed and 71 clinical samples) and correctly identified species and serotype in 100% and 84% of sequences, respectively. Known associations between specific serotypes and clinical syndromes are verified. Possible new associations are described to allow further independent testing.
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 43 12 شماره
صفحات -
تاریخ انتشار 2005